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Flatiron Health at ISPOR 2026

Philadelphia, PA
May 17-20, 2026
Booth #316

Flatiron is excited to attend and showcase our research at ISPOR 2026, validating exciting novel methodologies that will shape the future of evidence generation and health outcomes research in oncology.

Unlock critical evidence to accelerate access to cancer treatments worldwide

At Flatiron, we transform HEOR evidence for oncology's highest-stakes decisions. Our unified, global oncology engine combines the industry's highest-fidelity real-world data with expert-validated AI to turn complexity into clarity. 


With multinational data assets across the US, UK, Germany, and Japan—and a decade of strategic partnerships with regulators and HTAs—we deliver tailored, gold-standard evidence that payers and regulators trust. We calibrate our approach to match your specific evidence needs, whether navigating regulatory submissions, demonstrating value to payers, or addressing international market access.


Join our experts at Booth #316 to see how we translate evidence into confident decision-making that shapes the future of oncology access and advances patient care globally.

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Flatiron networking reception

Monday, May 18, 2026

7:00 - 10:00 PM ET

Join us for an evening of networking, cocktails, and hors d’oeuvres. This is a great opportunity to connect with colleagues, industry peers, and the Flatiron team.

 

Featured speaking session


Beyond Black Boxes: Transparent, Validated LLM Workflows for Accelerating Global HTA Submissions and Decisions

SESSION DETAILS

When: Wednesday, May 20, 10:00–11:00 AM ET

 

How do we ensure AI-powered tools generate reliable evidence? This session will explore validation frameworks that are customized for different uses—from extracting clinical data and physician insights to conducting network analyses and submitting evidence to regulators. Speakers will share real-world examples, including Flatiron’s VALID framework for assessing accuracy and the use of automation to speed up regulatory submissions in low- and middle-income countries. The discussion covers key challenges: keeping AI outputs transparent, maintaining clinical oversight, and communicating uncertainty. The goal: strengthen validation practices so AI can improve efficiency while preserving scientific rigor and supporting better decisions globally.

 

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lockwood-taylor

               

Lockwood Taylor

Senior Director, Head of Regulatory Strategy

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Our research

Read more about our accepted research at this year’s conference.


Poster presentations

Assessing quality of a LLM-derived prostate cancer (PC) real-world dataset: an application of the validation of accuracy for LLM/ML-extracted information and data (VALID) framework

Author Affiliations: Flatiron Health


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Date: May 18

Time: 4-7 PM

Poster Session: 2

Poster Code: MSR65



Real-world treatment patterns and outcomes in patients with 2L+ advanced or progressive endometrial cancer

Author Affiliations: Genmab, Swedish Cancer Institute, Flatiron Health


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Date: May 18

Time: 4-7 PM

Poster Session: 2

Poster Code: HSD38



Customization of a large language model approach to capture PSA and imaging derived real-world progression events in prostate cancer

Author Affiliations: Flatiron Health


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Date: May 19

Time: 4-7 PM

Poster Session: 4

Poster Code: RWD123




Evaluating model performance for between-country survival transportability

Author Affiliations: Flatiron Health


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See this research


Date: May 19

Time: 4-7 PM

Poster Session: 4

Poster Code: MSR169


From real-world data (RWD) to digital twins: Building models for patient-level counterfactual prediction in oncology

Author Affiliations: Flatiron Health


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See this research


Date: May 20

Time: 9-11:30 AM

Poster Session: 5

Poster Code: MSR219



External control arm feasibility across external data sources in oncology: Methodological and regulatory considerations

Author Affiliations: Friends of Cancer Research, Pancreatic Cancer Action Network, ConcertAI, AbbVie,Amgen, Medidata, Ontada, COTA Healthcare, iOMEDICO, Genentech, Flatiron Health, Aetion/Datavant, American Society of Clinical Oncology

Read the research

See this research


Date: May 20

Time: 9-11:30 AM

Poster Session: 5

Poster Code: RWD154



Featured solutions

 

A trusted leader in oncology real-world data and evidence generation, Flatiron supports life science partners in planning and executing RWE HEOR studies, particularly in support of HTA decision-making.

Learn more about our evidence solutions.

Real-world data

Our flexible real-world data configurations are tailored to address the specific needs of your oncology portfolio and now encompass more than 5 million patient journeys, 4 of the largest oncology markets in the world, 22+ tumor types, and multimodal data.

Real-world evidence services

Flatiron’s in-house expertise and flexible engagement models can help you generate the insights and evidence you need to advance your genitourinary cancer portfolio, from refining target product profiles, to conducting comparative effectiveness studies and supporting regulatory and HTA submissions.

 

Looking for support in designing and executing HEOR studies with RWE?

Leverage Flatiron’s industry leading multinational oncology data assets and expertise to drive your real-world studies, including:

  • Evaluating comparative- and cost-effectiveness 
  • Modeling long-term survival
  • Examining burden of illness
  • Analyzing treatment patterns
  • Qualitative understanding of clinical decision-making and prescribing behavior

Reach out to learn more about how we partner to accelerate patient access to oncology therapies across the globe

Request a meeting