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Flatiron Health at SABCS 2025

Flatiron is excited to attend and present our research at the 2025 San Antonio Breast Cancer Symposium, showcasing how our real-world data and research capabilities generate real-world insights that answer high priority research questions around treatment effectiveness, biomarker-driven approaches, clinical outcomes, and real-world access.

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Get a preview of our SABCS research presence from Catherine Keane, Senior Clinical Director at Flatiron

Flatiron is your trusted partner in delivering oncology evidence to support the evolving research questions across your breast cancer portfolio

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published pieces of breast cancer research

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Flatiron's foundational real-world data, flexibly designed to meet the needs of biopharma’s evolving research priorities with biomarker depth, scaled outcomes, and longitudinal data across our entire network of 5M+ patients.

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Our flexible real-world data configurations are tailored to address the specific needs of your oncology portfolio and now encompass more than 5 million patient journeys, 4 of the largest oncology markets in the world, 22+ tumor types, and multimodal data.

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Flatiron’s in-house expertise and flexible engagement models can help you generate the insights and evidence you need to advance your portfolio, from refining target product profiles, to conducting comparative effectiveness studies and supporting regulatory and HTA submissions.

Our research

Flatiron is excited to share our accepted research at this year’s conference.


Personalized acquired CDK4/6i resistance: Associations with baseline characteristics like obesity in real-world (RW) clinical-multiomics data

Spotlight poster presentation

 

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Presentation Number: PD3-02
Poster Spotlight 3
Presentation Date/Time: Wednesday, December 10, 2025, 7:33 AM - 7:36 AM
Location: 302 ABC

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Kristi Zimmerman Savill
Director, Scientific Engagement
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Racial/ethnic inequities in access to novel therapies and outcomes in triple negative breast cancer

Spotlight poster presentation

 

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Presentation Number: PD1-06
Poster Spotlight 1
Presentation Date/Time: Wednesday, December 10, 2025, 7:45 AM - 7:48 AM
Location: Hemisfair 3


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Olive Mbah
Senior Health Equity Scientist
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Real-world glucagon-like peptide-1 use and association with clinical characteristics, social determinants, and circulating tumor DNA positivity in patients with breast cancer

Spotlight poster presentation

 

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Presentation Number: PD8-08
Poster Spotlight 8
Presentation Date/Time: Thursday, December 11, 2025, 8:03 AM - 8:06 AM
Location: 221 ABC



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Olive Mbah
Senior Health Equity Scientist
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Real-world progression-free survival 2 (rwPFS2) and tumor response with CDK4/6is + aromatase inhibitor (AI) in patients (pts) with HR+/HER2– metastatic breast cancer (MBC)

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Presentation Number: PS1-11-10
Poster Session 1: Wednesday, December 10, 2025, 12:30 PM–2:00 PM




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Aaron Cohen, MD
Head of Research Oncology, Clinical Data
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Real-world treatment patterns and clinical outcomes in patients with emerging estrogen receptor 1 (ESR1)-mutated ER+ metastatic breast cancer in the U.S., 2018-2024

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Presentation Number: PS2-02-04
Poster Session 2: Wednesday, December 10, 2025, 5:00 PM - 6:30 PM





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James Roose
Senior Research Scientist
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Real-world treatment patterns in 1954 US patients with HER2-negative early breast cancer and germline BRCA mutations (2021–2025)

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Presentation Number: PS2-02-03
Poster Session 2: Wednesday, December 10, 2025, 5:00 PM - 6:30 PM

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Catherine Keane
Senior Clinical Director
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Real-world overall survival with palbociclib plus an aromatase inhibitor (AI) in patients with HR+/HER2− metastatic breast cancer (MBC) who are overweight/obese

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Presentation Number: PS2-04-12
Poster Session 2: Wednesday, December 10, 2025, 5:00 PM - 6:30 PM

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Melissa Estevez
Director, Research Sciences
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